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Key risk factors of vitamin B12 deficiency include: Decreased ability to absorb vitamins as a result of low hydrochloric acid secretion Certain medications Gastrointestinal disease and surgeries Vegans are also at a higher risk of vitamin B12 deficiency Can You Have Too Much Vitamin B12

Because methylcobalamin binds more efficiently to transport proteins, it is retained in the liver, kidneys, and nervous system for a significantly longer period

The most common example of an autoimmune condition is Pernicious Anemia , where the immune system attacks cells present in the stomach, which are responsible for producing intrinsic factors